TalkLeft has repeatedly warned against the federalization of crimes that can easily be prosecuted (or not, as a state chooses) under state law, most recently here and here. Conservatives who want to limit the scope of legislation authorized by the Commerce Clause will be disappointed by the Court's reinforcement of "Congress’ power to regulate purely local activities that are part of an economic 'class of activities' that have a substantial effect on interstate commerce." Unlike social conservatives who want to see greater federal regulation of private activity, "Commerce Clause conservatives" want to see no federal regulation of economic activity. Watching the two groups clash over the qualifications of the next Supreme Court nominee may be amusing.

For those less interested in constitutional theory, a more human focus on the problem of prosecuting patients who use marijuana to improve the quality of their lives can be found here. Critics of the administration's renewed war against marijuana smokers are quoted abundantly in this recent article.